The Waldispühl group is conducting research in RNA bioinformatics and cheminformatics. We develop combinatorial algorithms and machine learning frameworks to predict RNA 3D structures and their binding with small molecules. I also contributed to pioneer the use of video games to engage the public in genomic data analysis with Phylo (2010), Colony B (2016), Borderlands Science (2020) and Project Discovery Phase 3 (2020), which have gathered millions of citizen scientists worldwide.